Truxima

Truxima

Truxima (rituximab-abbs) is an FDA-approved biosimilar to Rituxan (Rituximab) used to treat adults with Rheumatoid Arthritis (RA) with another prescription medicine called methotrexate, to reduce the signs and symptoms of moderate to severe active RA, after treatment with at least one other medicine called a tumor necrosis factor (TNF) antagonist has been used and did not work well enough. It is also use to treat adults with Granulomatosis with Polyangiitis (GPA) (Wegener’s Granulomatosis) and Microscopic Polyangiitis (MPA): with glucocorticoids.

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Administration Information

Truxima is administered intravenously. One course of treatment includes 2 infusions given 2 weeks apart. Infusions generally take 4 to 6 hours. Truxima is typically administered every 6 months, or based on your doctor’s evaluation of your symptoms. If your symptoms return before it’s time for your next course, you and your physician may decide to treat earlier (but no sooner than 4 months).

Your doctor should check you for Hepatitis B before starting Truxima.

Your doctor may give you certain medicines before infusions to help reduce side effects such as acetaminophen and/or diphenhydramine HCI.

Helpful Resources

About Biosimilars:

Important Safety Information:

Resources & Support:

Preparing for Treatment:

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