Tysabri is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.
In a 2-year study of 627 people treated with Tysabri versus 315 people taking placebo, Tysabri was significantly more effective in slowing the progression of physical disability evaluated over a period of 12 weeks, reducing the formation of new active brain lesions, and reducing the number of relapses.
Tysabri in administered by intravenous infusion once every 28 days. The actual infusion takes about an hour. You’re then asked to stay for another hour just to make sure you’re not having an infusion-related reaction that may need medical attention.
Potential Side Effects
The most common side effects of Tysabri include headache, feeling tired, urinary tract infection, joint pain, lung infection, depression, pain in your arm and legs, diarrhea, vaginitis, rash, nose and throat infections, nausea, stomach area pain.
Tysabri increases the risk of progressive multifocal leukoencephalopathy (PML).
Your risk of getting PML is higher if you:
have been infected by the John Cunningham Virus (JCV). JCV is a common virus that is harmless in most people but can cause PML in people who have weakened immune systems, such as people taking Tysabri. Most people who are infected by JCV do not know it or do not have any symptoms. This infection usually happens in childhood. Before you start receiving Tysabri or during your treatment, your doctor may do a blood test to check if you have been infected by JCV.
have received Tysabri for a long time, especially longer than 2 years
have received certain medicines that can weaken your immune system before you start receiving Tysabri
Because of your risk of getting PML while you receive Tysabri, Tysabri is available only through a restricted distribution program called the TOUCH Prescribing Program.
For a full list of potential side effects, please see the Important Safety Information and Medication Guide on the Tysabri website.
Before you attend your first appointment at Sage Infusion, please make sure to review the documents below. The Patient Consent Form and HIPAA Privacy Authorization Form need to be filled out and signed ahead of your appointment, whereas the Notice of Privacy Practices and Patient Rights and Responsibilities are for reference only. Please contact us if you have any questions!
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